Cheap flights from Medellin to Panama City
Cheapest current fares: $216 in September 2026, 542 km direct flight in ~38m.
Cheapest month-by-month fares
Lowest available fare per calendar month from Medellin (MDE) to Panama City (PTY). Refreshed daily.
Medellin (MDE) → Panama City (PTY)
- September 2026 $216
- June 2026 $229
- August 2026 $235
Frequently asked questions
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What is the cheapest month to fly from Medellin to Panama City?
Based on current 6-month forward fare data, September 2026 is the cheapest month to fly from Medellin (MDE) to Panama City (PTY), with fares starting from $216.
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What is the lowest current fare from MDE to PTY?
The lowest currently-listed fare from Medellin (MDE) to Panama City (PTY) is $216 on 2026-09-18.
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How long is the flight from Medellin to Panama City?
Direct flights from MDE to PTY cover approximately 542 km (337 miles), with an estimated flight time of 38m. Operating airlines: CM.
Related guides for this route
Sibling pages — full route detail, airport overviews, visa context, per-airline routes.