Cheap flights from Medellin to Panama City

Cheapest current fares: $216 in September 2026, 542 km direct flight in ~38m.

Live fares · MDE → PTY

Cheapest month-by-month fares

Lowest available fare per calendar month from Medellin (MDE) to Panama City (PTY). Refreshed daily.

Medellin (MDE) → Panama City (PTY)

  1. September 2026 $216
  2. June 2026 $229
  3. August 2026 $235

Frequently asked questions

  • What is the cheapest month to fly from Medellin to Panama City?

    Based on current 6-month forward fare data, September 2026 is the cheapest month to fly from Medellin (MDE) to Panama City (PTY), with fares starting from $216.

  • What is the lowest current fare from MDE to PTY?

    The lowest currently-listed fare from Medellin (MDE) to Panama City (PTY) is $216 on 2026-09-18.

  • How long is the flight from Medellin to Panama City?

    Direct flights from MDE to PTY cover approximately 542 km (337 miles), with an estimated flight time of 38m. Operating airlines: CM.

Related guides for this route

Sibling pages — full route detail, airport overviews, visa context, per-airline routes.